Located just 0.6 km from Cala Porta Vecchia Public Beach, Palazzo Maio Hotel Monopoli is only 6 minutes on foot from Chiesa di Santa Maria del Suffragio detta del Purgatorio.

The centre of Monopoli is a 5 minutes' walk of the hotel. Museo e Sito Archeologico Cripta Romanica is just near the accommodation, and Karol Wojtyla airport is 65 km away. Nature lovers will appreciate the proximity to Cala Cozze, which is about 10 minutes' walk away. Castle of Carlo V is located merely 600 metres from this Monopoli hotel. There is Monopoli - Sant'Antonio bus stop within easy walking distance of Palazzo Maio Hotel.

Some of the air-conditioned rooms feature a television as well as a minibar.

A cooked-to-order breakfast is offered to guests daily. At a distance of 150 metres from the hotel, Il Ritrovo serves Italian dishes.